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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '494136ee14a9415568cc05e3aaaf8da2bb65dcfc230a9e3d18c934deb0e57492' 
  AND token = 'o4pyF2kD5UCl4OHYDEhCor8mH3GS/Pzn7DiRCYzzBsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}