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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2199ff0c219193262afcc4f6583479a5a15370087dd1051d8f206e5360d99748' 
  AND token = 'CGNcAGCoxxN3eQZxivTe4KumLfwiae0Lc/78nMCyit8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}