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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c40501134bb2667f883b7c3dd7ffa1ec3accbe35c9e924387e2fbafd760b74c' 
  AND token = '4wVwv2UjPcFGAsAWwc9QCVSX0dvx6r98WJjQ7E4BUUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}