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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4be8d6dc45b065e2f314239b2c4bfb9a28f76fb836e3d85f388c16d4a3324dd6' 
  AND token = 'n1XL509HpoRtJ79OERBr+n9fKKJ65UD/OMJ7/FL1VNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}