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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0371f5c484601c0bbd39c622afb446d3fbdeaf6f0c69101d4c0a08d8ad7dc61' 
  AND token = 'Dup62y4dAwLAQQn/SijrDlGzYrBG8iG+jYQM2IYZkD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}