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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e46f2b125af6d1cdd3e3ff2a1dae3c1460bd8cae27559b5e4f9b97d10db0bae6' 
  AND token = 'BHeZvLWbe6lfKRuN52IY2+BSHxUSKfE9TM1MbxHW6kM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}