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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b72c2fe72f1d158d4d63c8a3befb345279d9c0944a07127107c35c9531802bcb' 
  AND token = 'cPchuQC1IWonKQExRimnELDOmTVAHHenUjKoXb9hotk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}