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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd77092253e165c21cd2ef6f5618fc1223a62f1e79b3641acd71e9dc85bb6fac' 
  AND token = '7wVaQeC4AX4rVeaSo/gibD+D5p41/54TuV/h7ZP9jLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}