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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cb0b86ac6875170255f3fed00709deee488fca10ebbb0e29520df4b4d2ca5d2' 
  AND token = '8SwKVeKWvHLo2PaOIWrBy07CWDpNaxiT9VZqbBVWJAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}