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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c1bf69b2ba0e3640745c9096f9292fba1258244538d6ec55d76c8ff1ee14f3f' 
  AND token = 'jVV3w31VAhS9QUE89oEPRZkux9Vru7cRyyWPxeMm2sQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}