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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad6d44ac1a8f4b84b019feccffea8c7ea12e07846735c3f8d51ff57fada5240' 
  AND token = '2MIi5WmdrDMj2n065v/cYXmZriTdaHyLPBUrQThM3Yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}