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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bfcb9a15d2f5ba4efd3052d64dddc511d86a0cde2de4bee49c7b1c4b9c63f54' 
  AND token = 'BDnHFGqt6UlalbCtd22bFCsgx8xF+gYwl4P6JwnYE+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}