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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f146e1f2e18414d35d475a947a27a742a8dfe14a4a0a9b934a20730fd6f4b48' 
  AND token = 'LTWsqQvAhfHd5jm8mcu8EKw8v+vz9aR4EgZAdReE7Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}