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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfec50fb269269967884cef955e47c9538516d7d5624461b9dc86b2a189d6720' 
  AND token = 'EQyQq3tFxEbeeRbG8tRNKvZZatIFhpiS1VVBxt3TVxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}