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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a1400ce3af5e6f9aa7439ce2a2d1ce4be93cd8242b45bd4c8da68654cd1dfac' 
  AND token = 'LAvOI7Gs/mqSmUUopmgQd8dESA2F8y587oq4tcoxBeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}