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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06fd71c2355f5e65acd0c361ff05aa9f84630e0f39f0886a23dd24fdc053a9f1' 
  AND token = 'Lj/Vk7tYKhFS/wlwwokp46V+o8tCQrXyywjk0KXuwF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}