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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5ed03765c27ffceed34eceb645499c55b4cd78ffa49b76ec8467c63088d12d0' 
  AND token = 'FGd8/p1rc35Q2aHx+0Od/LJuVTOTmfUKo8jpC8Z04UA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}