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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b71e5a956d161894ff6ea15656b79e5f120ee81421df320cb016cdb708bd2a4d' 
  AND token = 'O66Qzzeeeoa/2Yh6vYsCvW8DRvj812I+M+4mSimNqBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}