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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e86467334f3931a37efc4751329b218e446da48d7c2d0bf370d2849106f2b0de' 
  AND token = 'tQ9spZqY5ceaRt9FKSscGQt0fwJVeIwEzh1XGo2kL74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}