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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd379d399a98f407defa329dfed20b1b32f9bce5fa2a9fe530e6035547c55981d' 
  AND token = 'TJMJLv3wKR+1hKmE0g/Q89v9byLeMfIDyVdtOvwtu5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}