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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b48ab98cb8b8d13af3024e95c6fffed316d0b6c2f88b7bea84402f95a6dba71' 
  AND token = '2IqOS5fBoB7eSNGuUiF8648JCsqi86BUjbMzeAuhLEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}