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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d5c65606e179dcb57ed5e8bd09dac0c5dce6de6a32fdf6b1a96210d0281ea58' 
  AND token = 'rSUHOo1rSy7vq8vPYuSDHc38lJKqgMGslpCqpc5aOow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}