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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad3dea64d8455ce5201f43b7383449f08154f1513fcab05ccf8dfe250b44da9' 
  AND token = 'oKKGlJBNAESw3k/wpEQxxkG7vpMs5ME5exbyv945qpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}