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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66425b97cca354c4323c715a056c7bdc752a1ec1d0e9b8aa0869f6b8154d1658' 
  AND token = 'N8INwrfv13yMSZar2VWQ+GrTEdAKkvP05furzEFH/tM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}