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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68b39a1b5bdcb719bb946d4cc6fdf373c0cf6c7d8fe8a6605571da88767eab11' 
  AND token = 'AmIG8RBRZB0/AQmfleQNmYzAiDvb96d6hiLSTjEbWX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}