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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e1f57676460802f7cd9314deacf0f7c87f1f2fc2005114bfca61b2993583dfb' 
  AND token = 'IZiLjEklC7oWxwOThDClBBycCdhG18T9i+IO5ytsUAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}