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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd52455546ab58886ba17b147e70b35edb038287ae9170f3917fe63b245ea8d2f' 
  AND token = '1n2DPBQ2AmWYggnPCNPmidCIXP2tr1lWluwUPlvLtWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}