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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de82f28e1695db0ab2a6253f18aa8f2dfcce6a34b1d1ab79897b172589ca07bc' 
  AND token = '45IDcAgTz8tVceVqPzDwaf0TKHIHIl3iZc2ETKgZCmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}