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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6124048e73c731234148b2b31e2bafcda9f782b5c0673165b2bc7ab6c88b4585' 
  AND token = 'JpEmB/ClJzGuLTsAAudGBpdoNmue1yLrdtHb8YV/5Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}