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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1dc6d21bd20eeef296dcccf270f460f8b15d60f929eeb87d2e0d0d9e1c6cb43' 
  AND token = 'eQ/haldDXxqKprPv6CRXVBOAMduSL+Aau1iyGLnuNYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}