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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bb53729387bb575547b814449599acb867aa6f6059430c39a90d7054688ae19' 
  AND token = 'lxvlAZw/xFzzMUwFn3vEg7RCE35QIDLVWeaH5vONkUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}