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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d2a963f12bc4a5091884f20e443ee710093fb342d4e0eec3330b04327c2b279' 
  AND token = 'Iuqr/iky0o1S5jeZcbjF/cL1gsnKX7jXmo1yGvoTqlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}