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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2b3abdcfeba43a952e824a9f203722ee9b6cedc0cd467f36afcd80b45af9d96' 
  AND token = 'J/P0v2mWjqa1vgTLO1l0KjmK9XqkPtc5w0Q+JccFKIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}