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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e658b2ec263fdec804f0b9e789b47887d9f208944223b72c3c8d131736d5e71d' 
  AND token = 'zSYU+bTUGpJkirNz2qdRa5hr+2Cq3uEAt42K0mlh3e0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}