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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f856a5cbf61a7f01ac07cdaa43c44c4d868a905d4b563419961dd75b0be0a07' 
  AND token = 'zJ2o5MZjTdcKjEjCHnvHbEuOjqPOPHznrccFRNUhMQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}