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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cad510468210f586c374853ff924d404134d0f5c1ea4ad1fbf903ad3ba7b2a8' 
  AND token = 'mcnG8RV3HJyycH/NnwrZU7rFbSGomF4+x4MTUmVDGBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}