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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '402661ed585a7f00e9d2a1792b5157cc5a39ca27b8eff3f2151d099fbbb9164c' 
  AND token = 'wz5uU1uWxTDcTxOH+iee5N2IW1utlQFD/tSF1FGdcfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}