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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34a47b4f067f3066935af2d17d7e3d44b9bd91bc56328a21eb2bbef96c0cffe2' 
  AND token = 'RR0GGobAZvcm+DGs7d2hHGDtBnFKF2NZ/pIxc3TNk9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}