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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ec3b3d0496790b72f76d9f08ff062bdb0cf621e370d1e8d01bc5700f68223dd' 
  AND token = 'jgXOrEQ3I18Z1zRXNWJ5bM+WkmUnR5xlT71sIbtU7jI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}